Sphera Funds Management Ltd.
CIK Number: 0001496201
Main Sectors:
Top Industries:
Filing Date: May 15, 2025
| Rank | Symbol | Name | Price | % Change | Shares | % Change Shares | Market Value | Avg. Price Paid | % Weight | Asset Type |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | TEVA | Teva Pharmaceut... | 17.61 | +0.28% | 1.57M | +0.19% | 24.16M | 15.07 | 5.56% | Share |
| 2 | TLT | iShares 20+ Yea... | 86.84 | +0.22% | 255.1K | +100.00% | 23.22M | 91.03 | 5.35% | Call |
| 3 | SNDX | Syndax Pharmace... | 15.74 | +2.24% | 1.66M | +20.47% | 20.44M | 16.69 | 4.71% | Share |
| 4 | SNY | Sanofi | 50.53 | +0.68% | 304.51K | -20.81% | 16.89M | 46.09 | 3.89% | Share |
| 5 | NVMI | Nova Ltd. | 246.46 | -1.17% | 90.7K | +33.09% | 16.72M | 200.34 | 3.85% | Share |
| 6 | AZN | AstraZeneca PLC | 80.52 | +1.23% | 175.06K | -22.22% | 12.87M | 54.48 | 2.96% | Share |
| 7 | BBIO | BridgeBio Pharm... | 48.88 | -0.06% | 366.61K | -59.5% | 12.67M | 24.55 | 2.92% | Share |
| 8 | SRPT | Sarepta Therape... | 20.58 | +1.98% | 157.93K | +59.65% | 10.08M | 107.9 | 2.32% | Share |
| 9 | RARE | Ultragenyx Phar... | 29.36 | +0.82% | 267.38K | +16.88% | 9.68M | 40.48 | 2.23% | Share |
| 10 | LLY | Eli Lilly and C... | 705.14 | +0.27% | 11.69K | -11.37% | 9.65M | 277.23 | 2.22% | Share |
| 11 | CLDX | Celldex Therape... | 20.89 | -13.03% | 507.83K | +7.11% | 9.22M | 33.4 | 2.12% | Share |
| 12 | JNJ | Johnson & Johns... | 178.84 | +0.59% | 52.83K | -24.34% | 8.76M | 161.01 | 2.02% | Share |
| 13 | NVO | Novo Nordisk A/... | 54.32 | -0.84% | 118.08K | +20.39% | 8.2M | 62.61 | 1.89% | Share |
| 14 | ELDN | Eledon Pharmace... | 2.58 | -1.53% | 2.31M | -9.58% | 7.82M | 3.3 | 1.80% | Share |
| 15 | MLYS | Mineralys Thera... | 15.48 | +6.98% | 465.53K | +144.15% | 7.39M | 14.48 | 1.70% | Share |
| 16 | AMZN | Amazon.com, Inc... | 223.81 | -1.84% | 36.61K | -41.53% | 6.96M | 152.7 | 1.60% | Share |
| 17 | ABBV | AbbVie Inc. | 209.11 | +1.42% | 30.26K | -11.68% | 6.34M | 111.45 | 1.46% | Share |
| 18 | PHVS | Pharvaris N.V. | 23.00 | -1.12% | 383.86K | -1.11% | 6.03M | 24.89 | 1.39% | Share |
| 19 | ORA | Ormat Technolog... | 92.29 | -0.41% | 84K | +6.33% | 5.94M | 67.9 | 1.37% | Share |
| 20 | CYTK | Cytokinetics, I... | 37.32 | -1.37% | 144.96K | -5.27% | 5.83M | 42.78 | 1.34% | Share |
| 21 | META | Meta Platforms,... | 747.72 | -0.5% | 9.96K | -52.56% | 5.74M | 371.88 | 1.32% | Share |
| 22 | NVS | Novartis AG | 127.23 | +1.82% | 50K | 0.00% | 5.57M | 87.06 | 1.28% | Share |
| 23 | MRK | Merck & Co., In... | 84.66 | -0.31% | 59.6K | 0.00% | 5.35M | 79.61 | 1.23% | Share |
| 24 | PRAX | Praxis Precisio... | 45.25 | +1.02% | 140.66K | +53.59% | 5.33M | 47.12 | 1.23% | Share |
| 25 | NICE | NICE Ltd. | 137.86 | -0.08% | 33.3K | -21.64% | 5.13M | 223.99 | 1.18% | Share |
| 26 | GSK | GSK plc | 40.08 | +1.15% | 130K | 0.00% | 5.04M | 35.22 | 1.16% | Share |
| 27 | SEDG | SolarEdge Techn... | 32.06 | +0.22% | 309.22K | -17.54% | 5M | 13.6 | 1.15% | Share |
| 28 | ETNB | 89bio, Inc. | 9.10 | +1.11% | 618.34K | +11.11% | 4.5M | 13.45 | 1.03% | Share |
| 29 | MRUS | Merus N.V. | 64.43 | +1.23% | 106.53K | -18.39% | 4.48M | 22.47 | 1.03% | Share |
| 30 | IMTX | Immatics N.V. | 5.60 | +0.18% | 921.11K | 0.00% | 4.15M | 11 | 0.96% | Share |
| 31 | APLS | Apellis Pharmac... | 26.58 | -0.39% | 181.35K | -12.08% | 3.97M | 28.84 | 0.91% | Share |
| 32 | MAZE | Maze Therapeuti... | 13.48 | +0.22% | 355.55K | +100.00% | 3.91M | 11.01 | 0.90% | Share |
| 33 | TVTX | Travere Therape... | 17.97 | +1.93% | 200K | -9.38% | 3.58M | 17.42 | 0.83% | Share |
| 34 | SVRA | Savara Inc. | 3.09 | +1.31% | 1.28M | +5.99% | 3.56M | 3.74 | 0.82% | Share |
| 35 | ARWR | Arrowhead Pharm... | 20.20 | +1.71% | 277.55K | +40.50% | 3.54M | 17.05 | 0.81% | Share |
| 36 | DYN | Dyne Therapeuti... | 11.97 | -2.29% | 329.26K | +39.36% | 3.44M | 21.98 | 0.79% | Share |
| 37 | ANNX | Annexon, Inc. | 2.14 | -2.28% | 1.76M | +41.94% | 3.41M | 4.18 | 0.78% | Share |
| 38 | JANX | Janux Therapeut... | 24.87 | +0.69% | 125.84K | +84.16% | 3.4M | 41.41 | 0.78% | Share |
| 39 | CYBN | Cybin Inc. | 6.61 | +0.30% | 527.22K | -2.02% | 3.34M | 8.89 | 0.77% | Share |
| 40 | IMVT | Immunovant, Inc... | 14.82 | -0.03% | 194.64K | +100.00% | 3.33M | 17.09 | 0.77% | Share |
| 41 | NVDA | NVIDIA Corporat... | 175.40 | -0.14% | 29.61K | +100.00% | 3.21M | 108.38 | 0.74% | Share |
| 42 | RZLT | Rezolute, Inc. | 6.66 | +2.94% | 1.08M | -7.24% | 3.14M | 3.68 | 0.72% | Share |
| 43 | RNA | Avidity Bioscie... | 44.34 | +0.73% | 106K | +100.00% | 3.13M | 29.52 | 0.72% | Share |
| 44 | AMGN | Amgen Inc. | 296.45 | +0.30% | 10K | +100.00% | 3.12M | 311.55 | 0.72% | Share |
| 45 | BIIB | Biogen Inc. | 138.99 | +0.09% | 22.74K | 0.00% | 3.11M | 249.27 | 0.72% | Share |
| 46 | ACOG | Alpha Cognition... | 8.00 | -1.17% | 596.99K | -3.71% | 3.02M | 5.89 | 0.70% | Share |
| 47 | VIGL | Vigil Neuroscie... | 8.05 | 0.00% | 1.6M | +6.79% | 2.86M | 3.22 | 0.66% | Share |
| 48 | NTLA | Intellia Therap... | 10.21 | -0.78% | 381.08K | -18.24% | 2.71M | 17.79 | 0.62% | Share |
| 49 | DAWN | Day One Biophar... | 6.81 | -0.15% | 334.99K | 0.00% | 2.66M | 11.94 | 0.61% | Share |
| 50 | AMAT | Applied Materia... | 160.96 | -0.77% | 18K | +100.00% | 2.61M | 145.12 | 0.60% | Share |
| 51 | SRRK | Scholar Rock Ho... | 34.40 | +14.21% | 78.19K | -13.3% | 2.51M | 8.01 | 0.58% | Share |
| 52 | CRM | Salesforce, Inc... | 246.58 | +0.24% | 9.1K | +100.00% | 2.44M | 268.36 | 0.56% | Share |
| 53 | BHVN | Biohaven Ltd. | 14.71 | -3.57% | 99.78K | -36.24% | 2.4M | 48.1 | 0.55% | Share |
| 54 | ENGN | enGene Holdings... | 3.86 | +1.58% | 528.37K | -5.65% | 2.37M | 6.65 | 0.55% | Share |
| 55 | SKYE | Skye Bioscience... | 3.50 | +5.11% | 1.48M | -5.64% | 2.35M | 7.35 | 0.54% | Share |
| 56 | WDAY | Workday, Inc. | 227.49 | -1% | 10K | 0.00% | 2.34M | 247.82 | 0.54% | Share |
| 57 | SWTX | SpringWorks The... | 46.99 | +0.02% | 52.01K | -47.99% | 2.3M | 36.13 | 0.53% | Share |
| 58 | PFE | Pfizer Inc. | 25.38 | +0.22% | 90K | 0.00% | 2.28M | 40.8 | 0.53% | Share |
| 59 | KURA | Kura Oncology, ... | 7.05 | -1.95% | 343.52K | -43.69% | 2.27M | 17.14 | 0.52% | Share |
| 60 | ELVN | Enliven Therape... | 19.66 | -0.51% | 111.74K | +100.00% | 2.2M | 19.68 | 0.51% | Share |
| 61 | TSEM | Tower Semicondu... | 50.05 | -0.54% | 61.55K | -62.96% | 2.19M | 33.6 | 0.51% | Share |
| 62 | UBER | Uber Technologi... | 93.74 | -1.66% | 30K | 0.00% | 2.19M | 60.32 | 0.50% | Share |
| 63 | GOOG | Alphabet Inc. | 200.19 | -1.14% | 13.5K | -68.97% | 2.11M | 190.44 | 0.49% | Share |
| 64 | VKTX | Viking Therapeu... | 25.69 | +5.46% | 83.27K | -19.37% | 2.01M | 63.31 | 0.46% | Share |
| 65 | COGT | Cogent Bioscien... | 11.87 | +0.89% | 335.02K | +100.00% | 2.01M | 5.99 | 0.46% | Share |
| 66 | VTGN | VistaGen Therap... | 3.10 | -2.21% | 790.55K | -2.23% | 1.98M | 5.15 | 0.46% | Share |
| 67 | AVGO | Broadcom Inc. | 291.17 | -1.27% | 11.7K | -30.72% | 1.96M | 161.37 | 0.45% | Share |
| 68 | IONS | Ionis Pharmaceu... | 42.81 | +0.78% | 63.82K | 0.00% | 1.93M | 47.11 | 0.44% | Share |
| 69 | NKE | NIKE, Inc. | 76.24 | -0.83% | 30.05K | +100.00% | 1.91M | 63.48 | 0.44% | Share |
| 70 | CHKP | Check Point Sof... | 189.29 | +0.69% | 8.33K | -76.61% | 1.9M | 192.81 | 0.44% | Share |
| 71 | RCKT | Rocket Pharmace... | 3.75 | +28.87% | 271.79K | 0.00% | 1.81M | 16.88 | 0.42% | Share |
| 72 | MSFT | Microsoft Corpo... | 505.72 | -0.79% | 4.59K | -79.43% | 1.72M | 332.68 | 0.40% | Share |
| 73 | NTR | Nutrien Ltd. | 57.03 | +0.43% | 30.89K | -44.73% | 1.53M | 51.7 | 0.35% | Share |
| 74 | GPCR | Structure Thera... | 18.57 | -1.25% | 84K | +100.00% | 1.45M | 17.31 | 0.33% | Share |
| 75 | WIX | Wix.com Ltd. | 126.92 | +0.24% | 8.8K | -77.58% | 1.44M | 144.89 | 0.33% | Share |
| 76 | FROG | JFrog Ltd. | 44.65 | -0.2% | 42.87K | -77.48% | 1.37M | 35.69 | 0.32% | Share |
| 77 | CAMT | Camtek Ltd. | 82.42 | -1.13% | 23.09K | -36.38% | 1.35M | 80.07 | 0.31% | Share |
| 78 | PMN | ProMIS Neurosci... | 0.52 | -7.1% | 1.93M | 0.00% | 1.34M | 1.96 | 0.31% | Share |
| 79 | SHLT | SHL Telemedicin... | 2.05 | +0.99% | 632.46K | 0.00% | 1.31M | 11.14 | 0.30% | Share |
| 80 | ORIC | ORIC Pharmaceut... | 9.51 | -0.94% | 234.83K | -14.05% | 1.31M | 9.09 | 0.30% | Share |
| 81 | CEVA | CEVA, Inc. | 22.20 | -2.03% | 48.92K | +100.00% | 1.25M | 25.61 | 0.29% | Share |
| 82 | BMY | Bristol-Myers S... | 48.26 | -0.17% | 20K | 0.00% | 1.22M | 56.56 | 0.28% | Share |
| 83 | VTYX | Ventyx Bioscien... | 2.56 | -2.66% | 1.01M | 0.00% | 1.16M | 4.97 | 0.27% | Share |
| 84 | NNDM | Nano Dimension ... | 1.36 | -1.45% | 717.52K | +100.00% | 1.14M | 1.59 | 0.26% | Share |
| 85 | INZY | Inozyme Pharma,... | 4.00 | +0.25% | 1.19M | 0.00% | 1.08M | 4.02 | 0.25% | Share |
| 86 | OTLK | Outlook Therape... | 2.39 | -9.13% | 857.14K | +100.00% | 1.05M | 1.22 | 0.24% | Share |
| 87 | ATXS | Astria Therapeu... | 6.31 | +0.16% | 189.8K | +35.77% | 1.01M | 8.75 | 0.23% | Share |
| 88 | CMMB | Chemomab Therap... | 0.91 | -2.47% | 900.43K | -25.86% | 981.47K | 1.57 | 0.23% | Share |
| 89 | MRVL | Marvell Technol... | 71.22 | -1.18% | 15.07K | -80.83% | 927.86K | 71.86 | 0.21% | Share |
| 90 | ARVN | Arvinas, Inc. | 7.10 | -0.56% | 125K | +100.00% | 877.5K | 7.02 | 0.20% | Share |
| 91 | XENE | Xenon Pharmaceu... | 37.64 | +0.75% | 26.1K | -49.91% | 875.55K | 39.2 | 0.20% | Share |
| 92 | PERI | Perion Network ... | 9.06 | -2.16% | 102.61K | 0.00% | 835.26K | 8.43 | 0.19% | Share |
| 93 | RGLS | Regulus Therape... | 8.16 | 0.00% | 452.85K | +100.00% | 792.48K | 1.75 | 0.18% | Share |
| 94 | LRMR | Larimar Therape... | 3.77 | +3.29% | 366.3K | -19.6% | 787.55K | 7.47 | 0.18% | Share |
| 95 | CRVS | Corvus Pharmace... | 5.19 | -0.38% | 205.86K | -58.87% | 654.63K | 5.35 | 0.15% | Share |
| 96 | HOWL | Werewolf Therap... | 1.24 | -2.36% | 626.81K | 0.00% | 609.38K | 16.55 | 0.14% | Share |
| 97 | VIR | Vir Biotechnolo... | 4.36 | -0.23% | 90.86K | -84.38% | 588.74K | 7.62 | 0.14% | Share |
| 98 | APRE | Aprea Therapeut... | 1.55 | -2.52% | 270K | 0.00% | 550.8K | 6.35 | 0.13% | Share |
| 99 | ZURA | Zura Bio Limite... | 1.75 | +1.16% | 421.23K | -39.02% | 543.38K | 4.06 | 0.13% | Share |
| 100 | KZR | Kezar Life Scie... | 3.90 | +0.52% | 108.47K | 0.00% | 529.35K | 6.72 | 0.12% | Share |
| 101 | JSPR | Jasper Therapeu... | 2.85 | +0.18% | 122.02K | -10.1% | 524.67K | 28.3 | 0.12% | Share |
| 102 | IBIT | iShares Bitcoin... | 64.90 | +1.11% | 8.15K | +100.00% | 381.5K | 46.81 | 0.09% | Share |
| 103 | CDTX | Cidara Therapeu... | 65.03 | +5.76% | 17.13K | +100.00% | 368.94K | 21.54 | 0.08% | Share |
| 104 | OKUR | OnKure Therapeu... | 2.73 | -0.36% | 80.45K | -7.9% | 345.95K | 8.6 | 0.08% | Share |
| 105 | FATE | Fate Therapeuti... | 1.13 | -0.88% | 397.18K | 0.00% | 313.81K | 1.65 | 0.07% | Share |
| 106 | CLYM | Climb Bio, Inc. | 2.25 | +11.39% | 241.94K | -3.97% | 295.16K | 6.23 | 0.07% | Share |
| 107 | ALEC | Alector, Inc. | 2.20 | +1.85% | 109.21K | -66.36% | 134.33K | 6 | 0.03% | Share |
| 108 | LVTX | LAVA Therapeuti... | 1.52 | +0.33% | 48.42K | -61.67% | 61.49K | 3.37 | 0.01% | Share |